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Last update: 15.06.2017
NRP 64: Nanoparticles in biodegradable implants: distribution and effects in brain tissue

In a collaboration with the Vetsuisse Faculty, the Institute for Chemistry and Bioanalytics of the University of Applied Sciences and Arts Northwestern Switzerland and the Group for Plastic Surgery of the Department of Clinical Research, we investigate the influence of nanoparticles on the health after they have been used for clinical treatment.

Due to their versatility, nanoparticles are used in many different fields in medicine and cosmetics. The influence of these particles on the health is not yet fully investigated, and the National Research Programme NRP 64 brings together various research groups in order to fill the gaps in the current knowledge. Our project aims to shed light on the paths the particles take after they have entered the body, and their influence on the tissue on the cellular level. We incubate cell cultures as well as fully functional neuronal tissue with custom made, medically relevant particles and track their whereabouts as well as their toxicity on the cells. This understanding will help to adapt particles for future use in the clinics to be unharmful and safe.